Remineralization of silver nanoparticle compound with sodium fluoride

Abstract

Introduction: In the last decade, pediatric dentistry treatments have been aimed at minimal invasion with the application of cariostatic and remineralizing compounds between others. Silver diamino fluoride has shown clinical efficacy with an undesirable side effect of pigmentation. The use of silver nanoparticles in combination with fluorides has also been proposed, for which there is little evidence on their properties to stop the carious process. Aim: To evaluate the remineralizing effect of a silver nanocomposite in combination with a fluoride varnish. Material and methods: With prior consent and information from the parents, a clinical study was carried out on 40 schoolchildren and 105 primary molars with ICDAS 3-6 carious lesions. After prophylaxis and advice on brushing technique, three applications were made one week between each one of a compound of silver nanoparticles plus a sodium fluoride varnish on the selected molars. The level of mineralization was determined before and after the intervention with the laser fluorescence method using the DIAGNOdent equipment. Means and standard deviation were obtained and Paired T test was performed for compare the data.  Results. Mineralization of the lesions was observed with a statistically significant difference: Baseline 55.7± 29; after the applications 38.9±19. p<0.001 There were no undesirable side effects. Conclusion. The compound of silver nanoparticles plus a fluoride varnish showed effectiveness in the remineralization and arrest of caries lesions